Melatonin ameliorates tau-related pathology via the miR-504-3p and CDK5 axis in Alzheimer’s disease

BACKGROUND: Intracellular accumulation of the microtubule-associated protein tau and its hyperphosphorylated forms is a key neuropathological feature of Alzheimer’s disease (AD). Melatonin has been shown to prevent tau hyperphosphorylation in cellular and animal models. However, the molecular mechan...

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Detalles Bibliográficos
Autores principales: Chen, Dongmei, Lan, Guihua, Li, Ruomeng, Mei, Yingxue, Shui, Xindong, Gu, Xi, Wang, Long, Zhang, Tao, Gan, Chen-Ling, Xia, Yongfang, Hu, Li, Tian, Yuan, Zhang, Mi, Lee, Tae Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082841/
https://www.ncbi.nlm.nih.gov/pubmed/35527277
http://dx.doi.org/10.1186/s40035-022-00302-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082841/
https://www.ncbi.nlm.nih.gov/pubmed/35527277
http://dx.doi.org/10.1186/s40035-022-00302-4

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