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An optimal variant to gene distance window derived from an empirical definition of cis and trans protein QTLs
BACKGROUND: A genome-wide association study (GWAS) correlates variation in the genotype with variation in the phenotype across a cohort, but the causal gene mediating that impact is often unclear. When the phenotype is protein abundance, a reasonable hypothesis is that the gene encoding that protein...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082853/ https://www.ncbi.nlm.nih.gov/pubmed/35527238 http://dx.doi.org/10.1186/s12859-022-04706-x |