Changes in glial cell phenotypes precede overt neurofibrillary tangle formation, correlate with markers of cortical cell damage, and predict cognitive status of individuals at Braak III-IV stages

Clinico-pathological correlation studies show that some otherwise healthy elderly individuals who never developed cognitive impairment harbor a burden of Alzheimer’s disease lesions (plaques and tangles) that would be expected to result in dementia. In the absence of comorbidities explaining such di...

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Detalles Bibliográficos
Autores principales: Taddei, Raquel N., Sanchez-Mico, Maria V., Bonnar, Orla, Connors, Theresa, Gaona, Angelica, Denbow, Dominique, Frosch, Matthew P., Gómez-Isla, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082857/
https://www.ncbi.nlm.nih.gov/pubmed/35534858
http://dx.doi.org/10.1186/s40478-022-01370-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082857/
https://www.ncbi.nlm.nih.gov/pubmed/35534858
http://dx.doi.org/10.1186/s40478-022-01370-3

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