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An integrative in-silico analysis discloses a novel molecular subset of colorectal cancer possibly eligible for immune checkpoint immunotherapy

BACKGROUND: Historically, the molecular classification of colorectal cancer (CRC) was based on the global genomic status, which identified microsatellite instability in mismatch repair (MMR) deficient CRC, and chromosomal instability in MMR proficient CRC. With the introduction of immune checkpoint...

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Detalles Bibliográficos
Autores principales: Sibilio, Pasquale, Belardinilli, Francesca, Licursi, Valerio, Paci, Paola, Giannini, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082922/
https://www.ncbi.nlm.nih.gov/pubmed/35534873
http://dx.doi.org/10.1186/s13062-022-00324-y