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Copper-mediated DNA damage caused by purpurin, a natural anthraquinone

BACKGROUND: Purpurin (1,2,4-trihydroxy-9,10-anthraquinone), a natural red anthraquinone pigment, has historically been used as a textile dye. However, purpurin induced urinary bladder tumors in rats, and displayed a mutagenic activity in assay using bacteria and mammalian cells. Many carcinogenic dy...

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Detalles Bibliográficos
Autores principales: Kobayashi, Hatasu, Mori, Yurie, Iwasa, Ryo, Hirao, Yuichiro, Kato, Shinya, Kawanishi, Shosuke, Murata, Mariko, Oikawa, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082958/
https://www.ncbi.nlm.nih.gov/pubmed/35527257
http://dx.doi.org/10.1186/s41021-022-00245-2