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Non-homologous End Joining-Mediated Insertional Mutagenesis Reveals a Novel Target for Enhancing Fatty Alcohols Production in Yarrowia lipolytica

Non-homologous end joining (NHEJ)-mediated integration is effective in generating random mutagenesis to identify beneficial gene targets in the whole genome, which can significantly promote the performance of the strains. Here, a novel target leading to higher protein synthesis was identified by NHE...

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Detalles Bibliográficos
Autores principales: Li, Mengxu, Zhang, Jinlai, Bai, Qiuyan, Fang, Lixia, Song, Hao, Cao, Yingxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082995/
https://www.ncbi.nlm.nih.gov/pubmed/35547152
http://dx.doi.org/10.3389/fmicb.2022.898884