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Overcoming Cancer Drug Resistance Utilizing PROTAC Technology

Cancer drug resistance presents a major barrier to continued successful treatment of malignancies. Current therapies inhibiting proteins indicated in cancer progression are consistently found to lose efficacy as a result of acquired drug resistance, often caused by mutated or overexpressed protein t...

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Detalles Bibliográficos
Autores principales: Burke, Matthew R., Smith, Alexis R., Zheng, Guangrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083012/
https://www.ncbi.nlm.nih.gov/pubmed/35547806
http://dx.doi.org/10.3389/fcell.2022.872729