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Energetic differences between non-domain-swapped and domain-swapped chain connectivities in the K2P potassium channel TRAAK

Two-pore domain (K2P) channels are twofold symmetric K(+) channels which control cell excitability by enabling the leak of potassium ions from cells in response to physicochemical stimuli. Crystallization of K2P channels revealed the presence of several structural features, which include an external...

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Detalles Bibliográficos
Autores principales: Navarro-Retamal, Carlos, Caballero, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083029/
https://www.ncbi.nlm.nih.gov/pubmed/35541058
http://dx.doi.org/10.1039/c8ra04159h