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Vitamin D Reverts the Exosome-Mediated Transfer of Cancer Resistance to the mTOR Inhibitor Everolimus in Hepatocellular Carcinoma

Several multi-kinase inhibitors were widely tested as potential first-line or second-line therapy in patients with advanced hepatocellular carcinoma (HCC). However, acquired drug resistance limits their clinical efficacy. Exosomes are microvesicles secreted by tumor and stromal cells that participat...

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Detalles Bibliográficos
Autores principales: Negri, Mariarosaria, Amatrudo, Feliciana, Gentile, Annalisa, Patalano, Roberta, Montò, Tatiana, de Angelis, Cristina, Simeoli, Chiara, Pirchio, Rosa, Auriemma, Renata Simona, Colao, Annamaria, Pivonello, Rosario, Pivonello, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083073/
https://www.ncbi.nlm.nih.gov/pubmed/35547877
http://dx.doi.org/10.3389/fonc.2022.874091