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Vitamin D Reverts the Exosome-Mediated Transfer of Cancer Resistance to the mTOR Inhibitor Everolimus in Hepatocellular Carcinoma
Several multi-kinase inhibitors were widely tested as potential first-line or second-line therapy in patients with advanced hepatocellular carcinoma (HCC). However, acquired drug resistance limits their clinical efficacy. Exosomes are microvesicles secreted by tumor and stromal cells that participat...
Autores principales: | Negri, Mariarosaria, Amatrudo, Feliciana, Gentile, Annalisa, Patalano, Roberta, Montò, Tatiana, de Angelis, Cristina, Simeoli, Chiara, Pirchio, Rosa, Auriemma, Renata Simona, Colao, Annamaria, Pivonello, Rosario, Pivonello, Claudia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083073/ https://www.ncbi.nlm.nih.gov/pubmed/35547877 http://dx.doi.org/10.3389/fonc.2022.874091 |
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