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SARM1 participates in axonal degeneration and mitochondrial dysfunction in prion disease

Prion disease represents a group of fatal neurogenerative diseases in humans and animals that are associated with energy loss, axonal degeneration, and mitochondrial dysfunction. Axonal degeneration is an early hallmark of neurodegeneration and is triggered by SARM1. We found that depletion or dysfu...

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Detalles Bibliográficos
Autores principales: Lai, Meng-Yu, Li, Jie, Zhang, Xi-Xi, Wu, Wei, Li, Zhi-Ping, Sun, Zhi-Xin, Zhao, Meng-Yang, Yang, Dong-Ming, Wang, Dong-Dong, Li, Wen, Zhao, De-Ming, Zhou, Xiang-Mei, Yang, Li-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083142/
https://www.ncbi.nlm.nih.gov/pubmed/35259852
http://dx.doi.org/10.4103/1673-5374.337051