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SARM1 participates in axonal degeneration and mitochondrial dysfunction in prion disease
Prion disease represents a group of fatal neurogenerative diseases in humans and animals that are associated with energy loss, axonal degeneration, and mitochondrial dysfunction. Axonal degeneration is an early hallmark of neurodegeneration and is triggered by SARM1. We found that depletion or dysfu...
Autores principales: | Lai, Meng-Yu, Li, Jie, Zhang, Xi-Xi, Wu, Wei, Li, Zhi-Ping, Sun, Zhi-Xin, Zhao, Meng-Yang, Yang, Dong-Ming, Wang, Dong-Dong, Li, Wen, Zhao, De-Ming, Zhou, Xiang-Mei, Yang, Li-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083142/ https://www.ncbi.nlm.nih.gov/pubmed/35259852 http://dx.doi.org/10.4103/1673-5374.337051 |
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