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Cranial irradiation impairs intrinsic excitability and synaptic plasticity of hippocampal CA1 pyramidal neurons with implications for cognitive function

Radiation therapy is a standard treatment for head and neck tumors. However, patients often exhibit cognitive impairments following radiation therapy. Previous studies have revealed that hippocampal dysfunction, specifically abnormal hippocampal neurogenesis or neuroinflammation, plays a key role in...

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Detalles Bibliográficos
Autores principales: Wu, Min-Yi, Zou, Wen-Jun, Yu, Pei, Yang, Yuhua, Li, Shao-Jian, Liu, Qiang, Xie, Jiatian, Chen, Si-Qi, Lin, Wei-Jye, Tang, Yamei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083168/
https://www.ncbi.nlm.nih.gov/pubmed/35259846
http://dx.doi.org/10.4103/1673-5374.336875