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The delivery of miR-21a-5p by extracellular vesicles induces microglial polarization via the STAT3 pathway following hypoxia-ischemia in neonatal mice

Extracellular vesicles (EVs) from mesenchymal stromal cells (MSCs) have previously been shown to protect against brain injury caused by hypoxia-ischemia (HI). The neuroprotective effects have been found to relate to the anti-inflammatory effects of EVs. However, the underlying mechanisms have not pr...

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Detalles Bibliográficos
Autores principales: Xin, Dan-Qing, Zhao, Yi-Jing, Li, Ting-Ting, Ke, Hong-Fei, Gai, Cheng-Cheng, Guo, Xiao-Fan, Chen, Wen-Qiang, Liu, De-Xiang, Wang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083169/
https://www.ncbi.nlm.nih.gov/pubmed/35259844
http://dx.doi.org/10.4103/1673-5374.336871