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The delivery of miR-21a-5p by extracellular vesicles induces microglial polarization via the STAT3 pathway following hypoxia-ischemia in neonatal mice
Extracellular vesicles (EVs) from mesenchymal stromal cells (MSCs) have previously been shown to protect against brain injury caused by hypoxia-ischemia (HI). The neuroprotective effects have been found to relate to the anti-inflammatory effects of EVs. However, the underlying mechanisms have not pr...
Autores principales: | Xin, Dan-Qing, Zhao, Yi-Jing, Li, Ting-Ting, Ke, Hong-Fei, Gai, Cheng-Cheng, Guo, Xiao-Fan, Chen, Wen-Qiang, Liu, De-Xiang, Wang, Zhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083169/ https://www.ncbi.nlm.nih.gov/pubmed/35259844 http://dx.doi.org/10.4103/1673-5374.336871 |
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