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Membrane partition of bis-(3-hydroxy-4-pyridinonato) zinc(ii) complexes revealed by molecular dynamics simulations

The class of 3-hydroxy-4-pyridinone ligands is widely known and valuable for biomedical and pharmaceutical purposes. Their chelating properties towards biologically-relevant transition metal ions highlight their potential biomedical utility. A set of 3-hydroxy-4-pyridinone Zn(ii) complexes at differ...

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Detalles Bibliográficos
Autores principales: Coimbra, João T. S., Brás, Natércia F., Fernandes, Pedro A., Rangel, Maria, Ramos, Maria J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083369/
https://www.ncbi.nlm.nih.gov/pubmed/35539964
http://dx.doi.org/10.1039/c8ra03602k