New ferrocene modified retinoic acid with enhanced efficacy against melanoma cells via GSH depletion

Malignant melanoma is a highly lethal disease, and advanced stages of melanoma have proven to be resistant to many chemotherapeutic drugs. Cancer stem cells (CSCs) and high levels of intracellular glutathione (GSH) have been proven to play important roles in drug resistance. Retinoic acid (RA) is a...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yibo, Sun, Bin, Han, Bin, Hu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083447/
https://www.ncbi.nlm.nih.gov/pubmed/35542710
http://dx.doi.org/10.1039/c8ra04078h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083447/
https://www.ncbi.nlm.nih.gov/pubmed/35542710
http://dx.doi.org/10.1039/c8ra04078h

Ejemplares similares