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New ferrocene modified retinoic acid with enhanced efficacy against melanoma cells via GSH depletion
Malignant melanoma is a highly lethal disease, and advanced stages of melanoma have proven to be resistant to many chemotherapeutic drugs. Cancer stem cells (CSCs) and high levels of intracellular glutathione (GSH) have been proven to play important roles in drug resistance. Retinoic acid (RA) is a...
Autores principales: | Wang, Yibo, Sun, Bin, Han, Bin, Hu, Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083447/ https://www.ncbi.nlm.nih.gov/pubmed/35542710 http://dx.doi.org/10.1039/c8ra04078h |
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