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Mechanisms Underlying Mu Opioid Receptor Effects on Parallel Fiber-Purkinje Cell Synaptic Transmission in Mouse Cerebellar Cortex

μ-opioid receptors (MOR) are widely expressed in the brain, varying in density in different areas. Activation of MORs underlies analgesia, euphoria, but may lead to tolerance, dependence, and ultimately opioid addiction. The Purkinje cell (PC) is the only efferent neuron in the cerebellar cortex and...

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Detalles Bibliográficos
Autores principales: Yang, Yi, Bai, Jin, Sun, Jia-yue, Ye, Ting, Zhang, Lu, Wu, Feng-ying, Nan, Jun, Lan, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083459/
https://www.ncbi.nlm.nih.gov/pubmed/35546898
http://dx.doi.org/10.3389/fnsyn.2022.862704