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High Tacrolimus Intrapatient Variability and Subtherapeutic Immunosuppression are Associated With Adverse Kidney Transplant Outcomes

Kidney transplant recipients with high intrapatient variability (IPV) in tacrolimus (Tac) exposure experience more rejection and reduced graft survival. To understand the underlying pathophysiology of this association, the authors investigated whether patients with high tacrolimus IPV have a more ac...

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Detalles Bibliográficos
Autores principales: Mendoza Rojas, Aleixandra, Hesselink, Dennis A., van Besouw, Nicole M., Dieterich, Marjolein, de Kuiper, Ronella, Baan, Carla C., van Gelder, Teun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Therapeutic Drug Monitoring 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083489/
https://www.ncbi.nlm.nih.gov/pubmed/35394988
http://dx.doi.org/10.1097/FTD.0000000000000955