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Visfatin inhibits colon cancer cell apoptosis and decreases chemosensitivity to 5-FU by promoting the SDF-1/CXCR4/Akt axis

5-Fluorouracil (5-FU) is the preferred chemotherapeutic drug used in the treatment of colon cancer; however, drug resistance affects its clinical efficacy. Visfatin, an adipokine that promotes tumour development, has the potential to increase resistance to chemotherapy. The present study aimed to ve...

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Detalles Bibliográficos
Autores principales: Zhao, Quan, Long, Yaxin, Cheng, Wen, Huang, Yingguang, Li, Jinyuan, Li, Yuejin, Li, Xing, Guo, Xiaodong, Li, Yu, Li, Guosan, Gong, Kunmei, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083850/
https://www.ncbi.nlm.nih.gov/pubmed/35506454
http://dx.doi.org/10.3892/ijo.2022.5365