Cargando…
Visfatin inhibits colon cancer cell apoptosis and decreases chemosensitivity to 5-FU by promoting the SDF-1/CXCR4/Akt axis
5-Fluorouracil (5-FU) is the preferred chemotherapeutic drug used in the treatment of colon cancer; however, drug resistance affects its clinical efficacy. Visfatin, an adipokine that promotes tumour development, has the potential to increase resistance to chemotherapy. The present study aimed to ve...
Autores principales: | Zhao, Quan, Long, Yaxin, Cheng, Wen, Huang, Yingguang, Li, Jinyuan, Li, Yuejin, Li, Xing, Guo, Xiaodong, Li, Yu, Li, Guosan, Gong, Kunmei, Zhang, Jian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083850/ https://www.ncbi.nlm.nih.gov/pubmed/35506454 http://dx.doi.org/10.3892/ijo.2022.5365 |
Ejemplares similares
-
Knockout of SIRT4 decreases chemosensitivity to 5-FU in colorectal cancer cells
por: Zhu, Yuanyuan, et al.
Publicado: (2018) -
Stem cells migration during skeletal muscle regeneration - the role of Sdf-1/Cxcr4 and Sdf-1/Cxcr7 axis
por: Kowalski, Kamil, et al.
Publicado: (2016) -
Transcription Factor TCF3 Promotes Macrophage-Mediated Inflammation and MMP Secretion in Abdominal Aortic Aneurysm by Regulating miR-143-5p/CCL20
por: Li, Yuejin, et al.
Publicado: (2023) -
Role of the HIF-1α/SDF-1/CXCR4 signaling axis in accelerated fracture healing after craniocerebral injury
por: Xue, Yonghua, et al.
Publicado: (2020) -
Leptin promotes bone metastasis of breast cancer by activating the SDF-1/CXCR4 axis
por: Duan, Lixia, et al.
Publicado: (2020)