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Combined systems pharmacology and fecal metabonomics to study the biomarkers and therapeutic mechanism of type 2 diabetic nephropathy treated with Astragalus and Leech

In our study, systems pharmacology was used to predict the molecular targets of Astragalus and Leech, and explore the therapeutic mechanism of type 2 diabetic nephropathy (T2DN) treated with Astragalus and Leech. Simultaneously, to reveal the systemic metabolic changes and biomarkers associated with...

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Detalles Bibliográficos
Autores principales: Chen, Ruiqun, Liao, Chengbin, Guo, Qian, Wu, Lirong, Zhang, Lei, Wang, Xiufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083881/
https://www.ncbi.nlm.nih.gov/pubmed/35540008
http://dx.doi.org/10.1039/c8ra04358b