Significance of rare variants in genes involved in the pathogenesis of Lynch syndrome

The molecular characterization of patients with Lynch syndrome (LS) involves germline testing to detect a deleterious mutation in one of the genes of the mismatch repair (MMR) pathway. To date, however, a large proportion of patients with a clinical suspicion of LS who undergo genetic testing do not...

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Detalles Bibliográficos
Autores principales: Liccardo, Raffaella, Lambiase, Matilde, Nolano, Antonio, De Rosa, Marina, Izzo, Paola, Duraturo, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083887/
https://www.ncbi.nlm.nih.gov/pubmed/35475445
http://dx.doi.org/10.3892/ijmm.2022.5137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083887/
https://www.ncbi.nlm.nih.gov/pubmed/35475445
http://dx.doi.org/10.3892/ijmm.2022.5137

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