Halogen bonding for the design of inhibitors by targeting the S1 pocket of serine proteases

Halogen bonding (or X bonding) has attracted increasing interest due to its significant role in molecular recognition in biological systems. Trypsin-like serine proteases have many physiological and pathophysiological functions. There is therefore extensive interest in generating specific inhibitors...

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Detalles Bibliográficos
Autores principales: Jiang, Longguang, Zhang, Xu, Zhou, Yang, Chen, Yayu, Luo, Zhipu, Li, Jinyu, Yuan, Cai, Huang, Mingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083945/
https://www.ncbi.nlm.nih.gov/pubmed/35542712
http://dx.doi.org/10.1039/c8ra03145b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083945/
https://www.ncbi.nlm.nih.gov/pubmed/35542712
http://dx.doi.org/10.1039/c8ra03145b

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