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Impact of Superoxide Dismutase Genetic Polymorphism (SOD2 Val16Ala) and Superoxide Dismutase Level on Disease Severity in a Cohort of Egyptian Sickle Cell Disease Patients

BACKGROUND: Oxidative stress plays a pivotal role in the pathophysiology of sickle cell disease (SCD) and its associated disease complications. Superoxide Dismutases (SODs) are protective enzymes against oxidative stress. SOD2 deficiency results in the accumulation of oxidized red cell proteins, inc...

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Detalles Bibliográficos
Autores principales: Khorshied, Mervat M., Shaheen, Iman A., Selim, Yasmeen M.M., Elshahawy, Asmaa O., Youssry, Ilham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083955/
https://www.ncbi.nlm.nih.gov/pubmed/35615333
http://dx.doi.org/10.4084/MJHID.2022.037