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CCN1 Promotes Inflammation by Inducing IL-6 Production via α6β1/PI3K/Akt/NF-κB Pathway in Autoimmune Hepatitis

Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease with unknown etiology. CCN1, an extracellular matrix-associated protein, is associated with carcinoma, inflammation, liver fibrosis, and even autoimmune diseases. However, the role that CCN1 plays in AIH has remained undetermined. In...

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Detalles Bibliográficos
Autores principales: Jiang, Renquan, Tang, Jifeng, Zhang, Xuehao, He, Yujue, Yu, Ziqing, Chen, Shuhui, Xia, Jinfang, Lin, Jinpiao, Ou, Qishui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084230/
https://www.ncbi.nlm.nih.gov/pubmed/35547732
http://dx.doi.org/10.3389/fimmu.2022.810671