The structure and configuration changes of multifunctional peptide vectors enhance gene delivery efficiency

We designed a series of peptide vectors that contain functional fragments with the goal of enhancing cellular internalization and gene transfection efficiency. The functional fragments included a cell-penetrating peptide (R(9)), a cationic amphiphilic α-helical peptide [(LLKK)(3)-H(6) or (LLHH)(3)],...

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Detalles Bibliográficos
Autores principales: Yang, Sen, Meng, Zhao, Kang, Ziyao, Sun, Chao, Wang, Taoran, Feng, Siliang, Meng, Qingbin, Liu, Keliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084241/
https://www.ncbi.nlm.nih.gov/pubmed/35542475
http://dx.doi.org/10.1039/c8ra04101f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084241/
https://www.ncbi.nlm.nih.gov/pubmed/35542475
http://dx.doi.org/10.1039/c8ra04101f

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