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The structure and configuration changes of multifunctional peptide vectors enhance gene delivery efficiency
We designed a series of peptide vectors that contain functional fragments with the goal of enhancing cellular internalization and gene transfection efficiency. The functional fragments included a cell-penetrating peptide (R(9)), a cationic amphiphilic α-helical peptide [(LLKK)(3)-H(6) or (LLHH)(3)],...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084241/ https://www.ncbi.nlm.nih.gov/pubmed/35542475 http://dx.doi.org/10.1039/c8ra04101f |