On the Utility of ToxCast-Based Predictive Models to Evaluate Potential Metabolic Disruption by Environmental Chemicals

BACKGROUND: Research suggests environmental contaminants can impact metabolic health; however, high costs prohibit in vivo screening of putative metabolic disruptors. High-throughput screening programs, such as ToxCast, hold promise to reduce testing gaps and prioritize higher-order (in vivo) testin...

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Detalles Bibliográficos
Autores principales: Filer, Dayne L., Hoffman, Kate, Sargis, Robert M., Trasande, Leonardo, Kassotis, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084331/
https://www.ncbi.nlm.nih.gov/pubmed/35533074
http://dx.doi.org/10.1289/EHP6779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084331/
https://www.ncbi.nlm.nih.gov/pubmed/35533074
http://dx.doi.org/10.1289/EHP6779

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