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On the Utility of ToxCast-Based Predictive Models to Evaluate Potential Metabolic Disruption by Environmental Chemicals
BACKGROUND: Research suggests environmental contaminants can impact metabolic health; however, high costs prohibit in vivo screening of putative metabolic disruptors. High-throughput screening programs, such as ToxCast, hold promise to reduce testing gaps and prioritize higher-order (in vivo) testin...
Autores principales: | Filer, Dayne L., Hoffman, Kate, Sargis, Robert M., Trasande, Leonardo, Kassotis, Christopher D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Environmental Health Perspectives
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084331/ https://www.ncbi.nlm.nih.gov/pubmed/35533074 http://dx.doi.org/10.1289/EHP6779 |
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