Livin participates in resistance to trastuzumab therapy for breast cancer through ERK1/2 and AKT pathways and promotes EMT-like phenotype

Trastuzumab resistance has emerged as a major issue in anti-human epidermal growth factor receptor-2 (HER2) therapy for breast cancers. The cell lines maintain overexpression of HER2. Upon treatment with trastuzumab, R-SKBR3 and R-BT474 cell lines displayed an increased growth rate and invasiveness,...

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Detalles Bibliográficos
Autores principales: Li, Fan, Zhang, Lu, Feng, Fan, Zheng, Ke, Li, YuJing, Wang, TieLin, Ren, GuoSheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084334/
https://www.ncbi.nlm.nih.gov/pubmed/35542453
http://dx.doi.org/10.1039/c8ra05727c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084334/
https://www.ncbi.nlm.nih.gov/pubmed/35542453
http://dx.doi.org/10.1039/c8ra05727c

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