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Revealing biomedically relevant cell and lectin type-dependent structure–activity profiles for glycoclusters by using tissue sections as an assay platform

The increasing realization of the involvement of lectin-glycan recognition in (patho)physiological processes inspires envisioning therapeutic intervention by high-avidity/specificity blocking reagents. Synthetic glycoclusters are proving to have potential for becoming such inhibitors but the commonl...

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Detalles Bibliográficos
Autores principales: Kaltner, Herbert, Manning, Joachim C., García Caballero, Gabriel, Di Salvo, Claudia, Gabba, Adele, Romero-Hernández, Laura L., Knospe, Clemens, Wu, Dan, Daly, Harrison C., O'Shea, Donal F., Gabius, Hans-Joachim, Murphy, Paul V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084366/
https://www.ncbi.nlm.nih.gov/pubmed/35542469
http://dx.doi.org/10.1039/c8ra05382k