Quality by design approach for green HPLC method development for simultaneous analysis of two thalassemia drugs in biological fluid with pharmacokinetic study

This work implements a combined experimental approach of analytical quality-by-design (AQbD) and green analytical chemistry (GAC) to develop an HPLC method for simultaneous determination of the two thalassemia drugs, deferasirox (DFX) and deferiprone (DFP), in biological fluid for the first time. Th...

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Detalles Bibliográficos
Autores principales: Fares, Michel Y., Hegazy, Maha A., El-Sayed, Ghada M., Abdelrahman, Maha M., Abdelwahab, Nada S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084420/
https://www.ncbi.nlm.nih.gov/pubmed/35548387
http://dx.doi.org/10.1039/d2ra00966h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084420/
https://www.ncbi.nlm.nih.gov/pubmed/35548387
http://dx.doi.org/10.1039/d2ra00966h

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