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Quality by design approach for green HPLC method development for simultaneous analysis of two thalassemia drugs in biological fluid with pharmacokinetic study
This work implements a combined experimental approach of analytical quality-by-design (AQbD) and green analytical chemistry (GAC) to develop an HPLC method for simultaneous determination of the two thalassemia drugs, deferasirox (DFX) and deferiprone (DFP), in biological fluid for the first time. Th...
Autores principales: | Fares, Michel Y., Hegazy, Maha A., El-Sayed, Ghada M., Abdelrahman, Maha M., Abdelwahab, Nada S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084420/ https://www.ncbi.nlm.nih.gov/pubmed/35548387 http://dx.doi.org/10.1039/d2ra00966h |
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