A novel and practical synthesis of CAT3: a phenanthroindolizidine alkaloid with potential in treating glioblastoma

CAT3, one of the (+)-deoxytylophorinine-based phenanthroindolizidine alkaloids, is a promising therapeutic agent for the treatment of hedgehog (Hh)-driven glioblastoma and is currently being evaluated in preclinical studies. In this paper, a novel and practical synthetic route for CAT3 was firstly d...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Ru-Bing, Lv, Hai-Ning, Zhu, Shan-Shan, Ren, Xiao-Dong, Xu, Song, Ma, Shuang-Gang, Liu, Yun-Bao, Qu, Jing, Yu, Shi-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084470/
https://www.ncbi.nlm.nih.gov/pubmed/35547992
http://dx.doi.org/10.1039/c8ra04511a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084470/
https://www.ncbi.nlm.nih.gov/pubmed/35547992
http://dx.doi.org/10.1039/c8ra04511a

Ejemplares similares