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Optimizing clinical dosing of combination broadly neutralizing antibodies for HIV prevention

Broadly neutralizing antibodies (bNAbs) are promising agents to prevent HIV infection and achieve HIV remission without antiretroviral therapy (ART). As with ART, bNAb combinations are likely needed to cover HIV’s extensive diversity. Not all bNAbs are identical in terms of their breadth, potency, a...

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Detalles Bibliográficos
Autores principales: Mayer, Bryan T., deCamp, Allan C., Huang, Yunda, Schiffer, Joshua T., Gottardo, Raphael, Gilbert, Peter B., Reeves, Daniel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084525/
https://www.ncbi.nlm.nih.gov/pubmed/35385469
http://dx.doi.org/10.1371/journal.pcbi.1010003