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Advances in the Structural and Physiological Functions of SHARPIN

SHARPIN was initially found as a SHANK-associated protein. SHARPIN can be used as an important component to form the linear ubiquitin chain assembly complex (LUBAC) with HOIL-1L, HOIP to produce a linear ubiquitin chain connected N-terminal Met1, playing a critical role in various cellular processes...

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Detalles Bibliográficos
Autores principales: Yu, Beiming, Wang, Feng, Wang, Yanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084887/
https://www.ncbi.nlm.nih.gov/pubmed/35547743
http://dx.doi.org/10.3389/fimmu.2022.858505