A bidirectional switch in the Shank3 phosphorylation state biases synapses toward up- or downscaling

Homeostatic synaptic plasticity requires widespread remodeling of synaptic signaling and scaffolding networks, but the role of post-translational modifications in this process has not been systematically studied. Using deep-scale quantitative analysis of the phosphoproteome in mouse neocortical neur...

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Detalles Bibliográficos
Autores principales: Wu, Chi-Hong, Tatavarty, Vedakumar, Jean Beltran, Pierre M, Guerrero, Andrea A, Keshishian, Hasmik, Krug, Karsten, MacMullan, Melanie A, Li, Li, Carr, Steven A, Cottrell, Jeffrey R, Turrigiano, Gina G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084893/
https://www.ncbi.nlm.nih.gov/pubmed/35471151
http://dx.doi.org/10.7554/eLife.74277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084893/
https://www.ncbi.nlm.nih.gov/pubmed/35471151
http://dx.doi.org/10.7554/eLife.74277

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