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A bidirectional switch in the Shank3 phosphorylation state biases synapses toward up- or downscaling
Homeostatic synaptic plasticity requires widespread remodeling of synaptic signaling and scaffolding networks, but the role of post-translational modifications in this process has not been systematically studied. Using deep-scale quantitative analysis of the phosphoproteome in mouse neocortical neur...
Autores principales: | Wu, Chi-Hong, Tatavarty, Vedakumar, Jean Beltran, Pierre M, Guerrero, Andrea A, Keshishian, Hasmik, Krug, Karsten, MacMullan, Melanie A, Li, Li, Carr, Steven A, Cottrell, Jeffrey R, Turrigiano, Gina G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084893/ https://www.ncbi.nlm.nih.gov/pubmed/35471151 http://dx.doi.org/10.7554/eLife.74277 |
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