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Apolipoprotein ε4 modifies obesity-related atrophy in the hippocampal formation of cognitively healthy adults

Characterizing age- and risk-related hippocampal vulnerabilities may inform about the neural underpinnings of cognitive decline. We studied the impact of three risk-factors, Apolipoprotein (APOE)-ε4, a family history of dementia, and central obesity, on the CA1, CA2/3, dentate gyrus and subiculum of...

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Detalles Bibliográficos
Autores principales: Coad, Bethany M., Ghomroudi, Parisa A., Sims, Rebecca, Aggleton, John P., Vann, Seralynne D., Metzler-Baddeley, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084919/
https://www.ncbi.nlm.nih.gov/pubmed/35303671
http://dx.doi.org/10.1016/j.neurobiolaging.2022.02.004