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Apolipoprotein ε4 modifies obesity-related atrophy in the hippocampal formation of cognitively healthy adults
Characterizing age- and risk-related hippocampal vulnerabilities may inform about the neural underpinnings of cognitive decline. We studied the impact of three risk-factors, Apolipoprotein (APOE)-ε4, a family history of dementia, and central obesity, on the CA1, CA2/3, dentate gyrus and subiculum of...
Autores principales: | Coad, Bethany M., Ghomroudi, Parisa A., Sims, Rebecca, Aggleton, John P., Vann, Seralynne D., Metzler-Baddeley, Claudia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084919/ https://www.ncbi.nlm.nih.gov/pubmed/35303671 http://dx.doi.org/10.1016/j.neurobiolaging.2022.02.004 |
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