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Endothelin-1-mediated miR-let-7g-5p triggers interlukin-6 and TNF-α to cause myopathy and chronic adipose inflammation in elderly patients with diabetes mellitus

Background: Diabetes and sarcopenia are verified as mutual relationships, which seriously affect the quality of life of the elderly. Endothelin-1 is well investigated, is elevated in patients with diabetes, and is related to muscle cellular senescence and fibrosis. However, the mechanism of ET-1 bet...

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Detalles Bibliográficos
Autores principales: Tsai, Chung-Huang, Huang, Pei-Ju, Lee, IT, Chen, Chien-Min, Wu, Min Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085227/
https://www.ncbi.nlm.nih.gov/pubmed/35468098
http://dx.doi.org/10.18632/aging.204034