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Claudin-5 relieves cognitive decline in Alzheimer’s disease mice through suppression of inhibitory GABAergic neurotransmission

Alzheimer’s disease (AD) is characterized by progressive cognitive decline, which is considered as the most common form of dementia in the elderly. Recently, it is suggested that impaired cerebrovascular function may precede the onset of AD. Claudin-5, which is the most enriched tight junction prote...

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Detalles Bibliográficos
Autores principales: Zhu, Ning, Wei, Meidan, Yuan, Linguang, He, Xiaodan, Chen, Chunli, Ji, Aimin, Zhang, Guozeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085235/
https://www.ncbi.nlm.nih.gov/pubmed/35471411
http://dx.doi.org/10.18632/aging.204029