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Structural modification of oridonin via DAST induced rearrangement

A simple and efficient protocol was developed for the syntheses of oridonin analogues, i.e. 6,20-epoxy ent-kaurane diterpenoid analogues from oridonin via diethylaminosulfur trifluoride (DAST) promoted rearrangement, most of which exhibited superior anticancer activities compared with their precurso...

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Detalles Bibliográficos
Autores principales: Luo, Dong-Dong, Peng, Kai, Yang, Jia-Yu, Piyachaturawat, Pawinee, Saengsawang, Witchuda, Ao, Lei, Zhao, Wan-Zhou, Tang, Yu, Wan, Sheng-Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085272/
https://www.ncbi.nlm.nih.gov/pubmed/35547324
http://dx.doi.org/10.1039/c8ra05728a