Identification of 4-isopropyl–thiotropolone as a novel anti-microbial: regioselective synthesis, NMR characterization, and biological evaluation

We have synthesized and separated tosylated thujaplicin isomers for the first time, and elucidated their structures using 1D, 2D-NMR techniques and X-ray crystallography. The tosylated isomers were used to synthesize 4-isopropyl–thiotropolone and 6-isopropyl–thiotropolone in a regioselective manner....

Descripción completa

Detalles Bibliográficos
Autores principales: Elagawany, Mohamed, Hegazy, Lamees, Cao, Feng, Donlin, Maureen J., Rath, Nigam, Tavis, John, Elgendy, Bahaa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085298/
https://www.ncbi.nlm.nih.gov/pubmed/35547306
http://dx.doi.org/10.1039/c8ra06297h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085298/
https://www.ncbi.nlm.nih.gov/pubmed/35547306
http://dx.doi.org/10.1039/c8ra06297h

Ejemplares similares