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Study of oxygen tension variation within live tumor spheroids using microfluidic devices and multi-photon laser scanning microscopy
Three-dimensional cell spheroid culture using microfluidic devices provides a convenient in vitro model for studying tumour spheroid structures and internal microenvironments. Recent studies suggest that oxygen deprived zones inside solid tumors are responsible for stimulating local cytokines and en...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085395/ https://www.ncbi.nlm.nih.gov/pubmed/35546825 http://dx.doi.org/10.1039/c8ra05505j |