Total synthesis of kealiiquinone: the regio-controlled strategy for accessing its 1-methyl-4-arylbenzimidazolone core

A practical, concise and straightforward total synthesis of kealiiquinone 1, a naphtho[2,3-d]imidazole alkaloid obtained from the Micronesian marine sponge Leucetta sp. was accomplished. The squaric acid chemistry to construct the 1,4-quinoid ring and the regioselective N-methylation through a benzo...

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Detalles Bibliográficos
Autores principales: Ramadoss, Velayudham, Alonso-Castro, Angel J., Campos-Xolalpa, Nimsi, Ortiz-Alvarado, Rafael, Yahuaca-Juárez, Berenice, Solorio-Alvarado, César R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085488/
https://www.ncbi.nlm.nih.gov/pubmed/35548717
http://dx.doi.org/10.1039/c8ra06676k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085488/
https://www.ncbi.nlm.nih.gov/pubmed/35548717
http://dx.doi.org/10.1039/c8ra06676k

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