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Total synthesis of kealiiquinone: the regio-controlled strategy for accessing its 1-methyl-4-arylbenzimidazolone core
A practical, concise and straightforward total synthesis of kealiiquinone 1, a naphtho[2,3-d]imidazole alkaloid obtained from the Micronesian marine sponge Leucetta sp. was accomplished. The squaric acid chemistry to construct the 1,4-quinoid ring and the regioselective N-methylation through a benzo...
Autores principales: | Ramadoss, Velayudham, Alonso-Castro, Angel J., Campos-Xolalpa, Nimsi, Ortiz-Alvarado, Rafael, Yahuaca-Juárez, Berenice, Solorio-Alvarado, César R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085488/ https://www.ncbi.nlm.nih.gov/pubmed/35548717 http://dx.doi.org/10.1039/c8ra06676k |
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