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Andrographolide inhibits human serum albumin fibril formations through site-specific molecular interactions

Protein misfolding and fibrillation are the fundamental traits in degenerative diseases like Alzheimer's, Parkinsonism, and diabetes mellitus. Bioactives such as flavonoids and terpenoids from plant sources are known to express protective effects against an array of diseases including diabetes,...

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Detalles Bibliográficos
Autores principales: Basu, Aalok, Bhayye, Sagar, Kundu, Sonia, Das, Aatryee, Mukherjee, Arup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9085492/
https://www.ncbi.nlm.nih.gov/pubmed/35548768
http://dx.doi.org/10.1039/c8ra04637a